Participate in clinical trials and help make the next generation of male contraception a reality!
Male Contraception Clinical Trials
New male contraceptive methods are on their way, with both hormonal and non-hormonal being tested in humans today. These in-human trials are critically important to ensuring the safety and efficacy of these new methods of contraception, and they provide an incredible opportunity for men and couples to be part of history as we usher in the next contraceptive revolution.
Male Contraceptive Initiative provides funding and advocacy support specifically for the development of non-hormonal, reversible male contraceptives, but we also believe in the need for sperm-producers to have an array of options so that they can choose what works best for them and in their relationship. To that end, we highlight opportunities for people to participate in clinical trials supporting male contraceptives across categories. Please reach out to us and let us know if you are aware of any clinical trials not featured here.
Non-hormonal Clinical Trials
YourChoice Therapeutics is exploring early-stage clinical research of their male contraceptive pill, YCT-529, a first-in-class, hormone-free, orally administered birth control pill for men and currently the only male pill that researchers are testing in humans. Visit their website for more details.
YCT-529 prevents sperm production by interfering with vitamin A metabolism in the testes.
Contraline is exploring early-stage clinical research of their vas-occlusive contraceptive ADAM™, which seeks to be the world’s first injectable hydrogel designed to provide men with long-lasting contraception. Contraline positions its product as being like the IUD, for men. Visit their website for more details.
Contraline’s hydrogel product blocks sperm from exiting the vas deferens.
Hormonal Clinical Trials
The National Institute of Child Health and Human Development (NICHD) is conducting clinical trials of numerous hormonal male contraceptive methods across the United States and in several sites globally.
Hormonal male contraceptive methods target the signaling systems for sperm production so that sperm counts are decreased, while maintaining all other male functions as normal.
Clinical trials include a Phase 2B combined hormonal gel that men apply daily to the skin of their shoulders. The gel contains both Nestorone® and Testosterone. Other products currently in testing include a hormonal male contraceptive injection and daily oral male contraceptive pills.
For more information and directions on how to sign up for trials, visit their website for more information. Visit their website for more information.
The hormonal gel is applied daily to a man’s shoulder.
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