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​Our Grantees

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A young man with short dark hair wearing a light blue button-up shirt stands against a plain white background, smiling softly at the camera.
Kevin Eisenfrats Co-Founder and CEO

$1,000,000 – Awarded December 2020

$200,000 – Awarded December 2018

Contraline

Charlottesville, VA

About

Contraline is a medical device company developing a long-lasting, non-hormonal, and reversible male contraceptive using advancements in hydrogel technology. The company was founded in 2015 by Kevin Eisenfrats and Dr. John Herr, and is headquartered in Charlottesville, Virginia.

Our Grant

Contraline has invented a proprietary hydrogel called ADAM™ that is implanted into the vas deferens through a minimally invasive, outpatient procedure. The hydrogel works by blocking sperm from traveling through the vas deferens. Similar to intrauterine devices (IUDs) for women, Contraline’s contraceptive is designed to last for years and be reversible.

MCI’s funding has been used by Contraline to initiate a clinical trial in Australia, where the product will be evaluated in men. Additional funds have been used by Contraline to refine the implantation procedure in preparation for filing with the FDA and initiating further clinical trials.

“Vas-occlusion is a promising non-hormonal male contraceptive approach that has been attempted for decades, yet no product has been realized. Our team has developed a vas-occlusive hydrogel that is easily injectable, safe, and long-lasting. We are constantly improving the product and procedure with a focus on clinical translation and patient satisfaction,” said Kevin Eisenfrats, Co-Founder and CEO of Contraline. “We are honored that MCI has chosen to partner with Contraline to bring the first long-lasting, non-hormonal, and reversible male contraceptive to market.”

Press Releases

Male Contraceptive Initiative Invests $1 Million in Contraline to Conduct Clinical Trial for Long-Lasting, Non-Hormonal Male Contraceptive​​
November 18, 2020

Announcing A $200K Grant To Contraline
January 24, 2019

More Information

Those interested in receiving updates about Contraline’s progress can sign up at https://www.contraline.com/participate/

A young man with short dark hair wearing a light blue button-up shirt stands against a plain white background, smiling softly at the camera.
Kevin Eisenfrats Co-Founder and CEO

$1,000,000 – Awarded December 2020

$200,000 – Awarded December 2018

Contraline

Charlottesville, VA

About

Contraline is a medical device company developing a long-lasting, non-hormonal, and reversible male contraceptive using advancements in hydrogel technology. The company was founded in 2015 by Kevin Eisenfrats and Dr. John Herr, and is headquartered in Charlottesville, Virginia.

Our Grant

Contraline has invented a proprietary hydrogel called ADAM™ that is implanted into the vas deferens through a minimally invasive, outpatient procedure. The hydrogel works by blocking sperm from traveling through the vas deferens. Similar to intrauterine devices (IUDs) for women, Contraline’s contraceptive is designed to last for years and be reversible.

MCI’s funding has been used by Contraline to initiate a clinical trial in Australia, where the product will be evaluated in men. Additional funds have been used by Contraline to refine the implantation procedure in preparation for filing with the FDA and initiating further clinical trials.

“Vas-occlusion is a promising non-hormonal male contraceptive approach that has been attempted for decades, yet no product has been realized. Our team has developed a vas-occlusive hydrogel that is easily injectable, safe, and long-lasting. We are constantly improving the product and procedure with a focus on clinical translation and patient satisfaction,” said Kevin Eisenfrats, Co-Founder and CEO of Contraline. “We are honored that MCI has chosen to partner with Contraline to bring the first long-lasting, non-hormonal, and reversible male contraceptive to market.”

Press Releases

Male Contraceptive Initiative Invests $1 Million in Contraline to Conduct Clinical Trial for Long-Lasting, Non-Hormonal Male Contraceptive​​
November 18, 2020

Announcing A $200K Grant To Contraline
January 24, 2019

More Information

Those interested in receiving updates about Contraline’s progress can sign up at https://www.contraline.com/participate/

Contraline: Advancing Long-Lasting, Reversible Male Contraception with Hydrogel Technology
Developing the “male IUD” with Kevin Eisenfrats from Contraline
Contraceptive gel for men in clinical trials says Virginia company

Publications

Matsumoto NM, Chiartas TG, Paysour BR, Barry TJ, Ott LE, Tropsha Y, Eisenfrats KS. Preclinical development of a novel injectable hydrogel for vas-occlusion. Contraception. 2025 Feb 10:110839. doi: 10.1016/j.contraception.2025.110839. Epub ahead of print. PMID: 39938674.

Khourdaji, Iyad, Jacqueline Zillioux, Kevin Eisenfrats, Daniel Foley, and Ryan Smith. “The Future of Male Contraception: A Fertile Ground.” Translational Andrology and Urology 7, no. S2 (May 2018): S220–35. https://doi.org/10.21037/tau.2018.03.23.

Meet MCI's Grantees & Fellows!

Our grantees and fellows represent some of the finest minds in the male contraception research community from around the world.

At Male Contraceptive Initiative, we prioritize funding research that aligns with our mission of driving male contraception closer to clinical trials. We strategically allocate our resources to support a diverse range of projects, focusing on non-hormonal and reversible methods that have the potential to meet the needs of a broader population. Our goal is to catalyze progress in this field and bring innovative male birth control options to market.

Discover the innovative research being conducted by our grantees and fellows by clicking on the buttons below:

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