Our Grantees

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Ethan D. Goddard-Borger, PhD Professor

$200,000 / 2 years – Awarded 2024

The Walter and Eliza Hall Institute of Medical Research (WEHI)

Parkville, Australia

About

Professor Ethan D. Goddard-Borger is a leading scientist in drug discovery and chemical biology, with extensive experience in developing small-molecule inhibitors against challenging therapeutic targets. His expertise in enzyme biochemistry, glycobiology, and structural biology, combined with his passion for developing new contraceptive options makes him ideally positioned to lead this innovative project.

Our Grant

Male Contraceptive Initiative is thrilled to support Professor Goddard-Borger’s research on DPY19L2 as a target for male contraception. This project aligns with our mission to fund cutting-edge research that can lead to safe, effective, and reversible contraceptive options for men.

A New Approach to Male Contraception: Dr. Goddard-Borger's DPY19L2 Project

Publications

Bloch JS, John A, Mao R, Mukherjee S, Boilevin J, Irobalieva RN, Darbre T, Scott NE, Reymond J-L, Kossiakoff AA, Goddard-Borger ED*, Locher KP* Structure, sequon recognition, and mechanism of tryptophan C mannosyltransferase. Nat Chem Biol, 2023 19(5), 575-584. doi: 10.1038/s41589-022-01219-9.

John A, Järvå MA, Shah S, Mao R, Chappaz S, Birkinshaw RW, Czabotar PE, Lo AW, Scott NE, Goddard-Borger ED* Yeast- and antibody-based tools for studying tryptophan C- mannosylation. Nat Chem Biol, 2021 17(4):428-437. doi: 10.1038/s41589-020-00727-w.

Celse T, Cazin C, Mietton F, et al. Genetic analyses of a large cohort of infertile patients with globozoospermia, DPY19L2 still the main actor, GGN confirmed as a guest player. Hum Genet, 2021 140(1):43-57. doi: 10.1007/s00439-020-02229-0.

Meet MCI's Grantees & Fellows!

Our grantees and fellows represent some of the finest minds in the male contraception research community from around the world.

At Male Contraceptive Initiative, we prioritize funding research that aligns with our mission of driving male contraception closer to clinical trials. We strategically allocate our resources to support a diverse range of projects, focusing on non-hormonal and reversible methods that have the potential to meet the needs of a broader population. Our goal is to catalyze progress in this field and bring innovative male birth control options to market.

Discover the innovative research being conducted by our grantees and fellows by clicking on the buttons below:

MCI'S GRANTEES

MCI'S FELLOWS

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