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Male Contraceptive Initiative ​Organizational Overview

A table with sticky notes; one reads Why Not Now? and another reads Why Not Us? Several blank sticky notes are also on the table. The image is in black and white.

We provide funding and advocacy support for male contraception research and development.​

Male Contraceptive Initiative (MCI) is a 501(c)(3) non-profit organization based in Durham, North Carolina, USA and founded in 2014. We provide research and advocacy support for the development of new methods of non-hormonal, reversible male contraceptives in order to empower men and couples with the resources they need to meaningfully and equitably contribute to family planning goals.

Infographic titled Theory of Change: Achieving Reproductive Autonomy with Male Contraception showing a flowchart of inputs, outputs, outcomes, and impacts of developing new male contraceptive methods.

Male Contraceptive Initiative’s Theory of Change

“It’s not a female reproductive rights issue; it’s not a male reproductive rights issue. It’s a human issue.”

– Devin Patterson, Data Architect

We believe in and advocate for "Reproductive Autonomy for All".

Male Contraceptive Initiative’s vision is “Reproductive Autonomy for All”, and it is rooted in the foundation of the hopeful reality we work diligently to achieve: a world where everyone has the resources necessary for reproductive freedom.

While reproduction takes two people, the responsibilities, and subsequently resources, for family planning are overwhelmingly focused on women. This imbalance has far-reaching implications, negatively affecting issues as diverse as gender dynamics as well as rates of unintended pregnancies. Both egg- and sperm-producers need access to a robust method mix of contraceptives to meaningfully bring balance to contraceptive access and responsibility. We cannot have reproductive autonomy for anyone without contraception for everyone.

Male Contraceptive Initiative’s focus is on supporting the development of new forms of non-hormonal, reversible male contraceptives. We do this through funding and advocacy efforts, and we envision these novel contraceptives as tools that empower humans of all gender identities and sexual orientations.

Text on a white background reads: Reproductive Autonomy for All. The word All is in orange, while the rest of the text is in dark blue.

Male Contraceptive Initiative’s Vision Statement

“Never doubt that a small group of thoughtful, committed citizens can change the world; indeed, it’s the only thing that ever has.”

– Margaret Mead, Cultural Anthropologist

​We fund research developing the next generation of male contraceptives.

At Male Contraceptive Initiative, we believe that new ideas can come to fruition in many ways. We support scientists, students, and researchers across the globe, working in academia, private industry, and the nonprofit sector.

Our grant portfolio of long and short term funding opportunities in the field accelerate the development of contraceptives like devices that can last for years, on-demand contraceptives, implants that can deliver contraceptives over time, daily pills, and more. Through our Contraceptive Accelerator Network, we take on the development of specific projects with a mission-centric approach that ensures promising non-hormonal, reversible contraceptive targets receive the support necessary to develop them as next generation birth control methods delivered to those who produce sperm. The Contraceptive Accelerator Network, LLC was spun out from MCI as a wholly owned, for profit subsidiary with $1.0M in private investment. Other areas of investment include moonshot projects and early career support for young investigators.

A chart titled Male Contraceptive Initiatives Funding shows funding focus areas—Professional Development, Innovation, Progress, and Collaboration—with specific awards and programs listed under each category in a grid format.

Male Contraceptive Initiative’s Funding Mechanisms

“Contraception in general is one of the best ways to both give people rights at the same time as you’re saving the planet. Because you give people the choice to do what they want.”

– Elaine Lissner, Founder, Parsemus Foundation

At Male Contraceptive Initiative, we understand the existing problems with family planning methods and work towards creating meaningful, lasting solutions.

PROBLEMS

  • There are ~121 million unintended pregnancies per year globally but current contraceptive options focus on only half of the population
  • Couples want more resources to help them prevent or delay pregnancy
  • The current contraceptive method mix is predominantly female and hormonal
  • Burden falls to women with undesirable side effects, safety concerns, no reversible, long-acting options for men, and a high level of unmet need

SOLUTION

  • Expand contraceptive method mix to include non-hormonal, reversible male contraceptive methods in order to:
    • Provide equitable contraceptive options for men & women
    • Allow couples to share responsibility for contraception
    • Provide choices in methods across reproductive life-stages
    • Develop a favorable safety profile with fewer side effects than hormonal methods
An infographic titled The Male Contraceptive Development Pipeline illustrates four stages: spermatogenesis, sperm motility, sperm transport, and fertilization, each with icons and brief descriptions, on a blue and gray background.

The Development Pipeline

“As a mom of teenagers, I think that male contraception is just going to be an invaluable tool for prevention for men, as well as for women.”

– Bethany Young Holt, Executive Director and Founder, CAMI Health & Initiative for MPTs

 

Male Contraceptive Initiative's approach is to facilitate collaboration amongst researchers to share resources and maximize fundraising potential in order to accelerate the time to market for new male contraceptives.

We seek to accomplish this by:

  • Providing grants to support research & development efforts
  • Investing in promising targets and companies developing new male contraceptives
  • Driving advocacy efforts to increase investor and public support
  • Incentivizing researchers to transition from competing for limited funding to working together to maximize fund-raising potential and expedite development timelines
  • Supporting a small field of dedicated scientists collaborating to move the field further faster

As a small, nimble nonprofit, we rely heavily on the support of engaged and enthusiastic partners to achieve our objectives. We understand the importance, and potential impact, of every dollar, and we appreciate the timelines and constraints that our grantees face. We seek like-minded partners aligned with our vision and passionate about creating real impact in the world.​​

A flowchart for the Male Contraceptive Initiative (MCI) shows orange central circle connected to blue circles labeled Partners, Future Users, General Public, Developers, and Funders, each with related subgroups.