Market Publications
What About Methods for Men? A Qualitative Analysis of Attitudes Toward Male Contraception in Burkina Faso and Uganda
Male Contraceptive Initiative provided grant funding for this publication, derived from qualitative data taken from focus group discussions with 80 men aged 23–67 and 398 women aged 15–50 conducted in Burkina Faso and Uganda in 2016. It concludes that the acceptability of new male methods among most participants in the two countries indicates a potential demand for male contraceptives. Options should include a variety of method characteristics to maximize choice, engage men, and support men and women's contraceptive needs.
Male Contraceptive Initiative provided grant funding for this publication, derived from qualitative data taken from focus group discussions with 80 men aged 23–67 and 398 women aged 15–50 conducted in Burkina Faso and Uganda in 2016. It concludes that the acceptability of new male methods among most participants in the two countries indicates a potential demand for male contraceptives. Options should include a variety of method characteristics to maximize choice, engage men, and support men and women's contraceptive needs.
Consumer Research Study
Male Contraceptive Initiative led a study to identify unmet needs and satisfaction with current contraceptive methods among a sample of men across key market segments. To the best of our knowledge, this is the largest survey in the United States in the last ten years exclusive to sexually active men ages 18-44 to better understand their attitudes, needs and motivations regarding the future of male contraception as a family planning method.
Male Contraceptive Initiative led a study to identify unmet needs and satisfaction with current contraceptive methods among a sample of men across key market segments. To the best of our knowledge, this is the largest survey in the United States in the last ten years exclusive to sexually active men ages 18-44 to better understand their attitudes, needs and motivations regarding the future of male contraception as a family planning method.
Enhanced Discovery Scan
Male Contraceptive Initiative worked with YTH to explore the body of existing knowledge around male contraception and generate novel solutions for furthering effective development and user engagement in this area. This Executive Summary shares key findings from the study, as well as details on the study’s aims and methodology.
Male Contraceptive Initiative worked with YTH to explore the body of existing knowledge around male contraception and generate novel solutions for furthering effective development and user engagement in this area. This Executive Summary shares key findings from the study, as well as details on the study’s aims and methodology.
Scientific Publications
Vahdat, Heather L, Kevin Shane, and Logan M Nickels, "The Role of Team Science in the Future of Male Contraception†." Biology of Reproduction, 2020.
Campelia, Georgina D., Carmen Abbe, Logan M. Nickels, Evy McElmeel, and John K. Amory, '"Shared Risk": Reframing Risk Analysis in the Ethics of Novel Male Contraceptives', Contraception, 2020.
Dorman, Emily, et al. “Modeling the impact of novel male contraceptive methods on reductions in unintended pregnancies in Nigeria, South Africa, and the United States.” Contraception 97.1 (2018): 62-69.
MCI Publications
Male Contraceptive Initiative's Vision & Mission
An organization’s vision, mission, and principles are its heart and soul. They act as the North Star that guides all organizational activities, from strategy to execution. Male Contraceptive Initiative developed these defining organizational statements in a deliberate, intentional manner in order to articulate not just our motivations and principles, but also our desired impact and the steps we take towards realizing it. This publication details our vision and mission statements, as well how they extrapolate into our core organizational principles and align with our strategic activities.
An organization’s vision, mission, and principles are its heart and soul. They act as the North Star that guides all organizational activities, from strategy to execution. Male Contraceptive Initiative developed these defining organizational statements in a deliberate, intentional manner in order to articulate not just our motivations and principles, but also our desired impact and the steps we take towards realizing it. This publication details our vision and mission statements, as well how they extrapolate into our core organizational principles and align with our strategic activities.
Male Contraception Ideation Event Report
MCI invited leaders in male contraception, and from other fields of practice to contribute their knowledge and experience to brainstorm potential solutions to the persistent challenges in the field of male contraceptive research and development over the course of a 3-day ideation event at the IDEO offices in San Francisco. This report shares details about and outcomes from the event.
MCI invited leaders in male contraception, and from other fields of practice to contribute their knowledge and experience to brainstorm potential solutions to the persistent challenges in the field of male contraceptive research and development over the course of a 3-day ideation event at the IDEO offices in San Francisco. This report shares details about and outcomes from the event.
Male Contraception Initiative’s 2019 Annual Report
MCI had a tremendous year in 2019 thanks to your generous support. This annual report shares details about all that we were able to accomplish together.
MCI had a tremendous year in 2019 thanks to your generous support. This annual report shares details about all that we were able to accomplish together.
MCI Grantee Publications
Male Contraceptive Initiative engages with and supports a diverse, international research community working to make new methods of non-hormonal, reversible male contraceptives a reality. Our grantees represent decades of experience in scientific enquiry that span multiple research areas. As such, there is an extensive body of work attributable to them. In this section, we highlight only the publications of our grantees that are directly attributable to MCI’s support.
3D in situ imaging of the female reproductive tract reveals molecular signatures of fertilizing spermatozoa in mice
Lukas Ded, Jae Yeon Hwang, Kiyoshi Miki, Huanan F Shi, Jean-Ju Chung. '3D in situ imaging of the female reproductive tract reveals molecular signatures of fertilizing spermatozoa in mice,' eLife, 2020
What About Methods for Men? A Qualitative Analysis of Attitudes Toward Male Contraception in Burkina Faso and Uganda
Alice F. Cartwright, Anna Lawton, Aurélie Brunie and Rebecca L. Callahan. 'What About Methods for Men? A Qualitative Analysis of Attitudes Toward Male Contraception in Burkina Faso and Uganda,' International Perspectives on Sexual and Reproductive Health , 2020, Vol. 46 (2020), pp. 153-162
Synthesis of 2-phenyl-5,6,7,8-tetrahydroquinoxaline derivatives and screening for P2X1-purinoreceptor antagonist activity in isolated preparations of rat vas deferens, for translation into a male contraceptive
Mathiew M, Dennis B, Bennetts F, Su E, Nguyen N, Botteon A, Baell J, Ventura S. 'Synthesis of 2-phenyl-5,6,7,8-tetrahydroquinoxaline derivatives and screening for P2X1-purinoreceptor antagonist activity in isolated preparations of rat vas deferens, for translation into a male contraceptive,' Biology of Reproduction, 2020.
The Impact of Di-2-Ethylhexyl Phthalate on Sperm Fertility
Liliya Gabelev Khasin, John Della Rosa, Natalie Petersen, Jacob Moeller, Lance J. Kriegsfeld, and Polina V. Lishko, ‘The Impact of Di-2-Ethylhexyl Phthalate on Sperm Fertility,’ Frontiers in Cell and Developmental Biology, 2020,
Optimization of Lead Compounds Into On-Demand, Non-Hormonal Contraceptives: Leveraging a Public-Private Drug Discovery Institute Collaboration
Balbach, Melanie, Makoto Fushimi, David J Huggins, Clemens Steegborn, Peter T Meinke, Lonny R Levin, et al., ‘Optimization of Lead Compounds into On-Demand, Nonhormonal Contraceptives: Leveraging a Public–Private Drug Discovery Institute Collaboration†’, Biology of Reproduction, 2020.
HIPK4 is Essential for Murine Spermiogenesis
J Aaron Crapster, Paul G Rack, Zane J Hellmann, Austen D Le, Christopher M Adams, Ryan D Leib, Joshua E Elias, John Perrino, Barry Behr, Yanfeng Li, Jennifer Lin, Hong Zeng, James K Chen. 'HIPK4 is Essential for Murine Spermiogenesis,' eLife 2020
3D in situ imaging of the female reproductive tract reveals molecular signatures of fertilizing spermatozoa in mice
Lukas Ded, Jae Yeon Hwang, Kiyoshi Miki, Huanan F Shi, Jean-Ju Chung. '3D in situ imaging of the female reproductive tract reveals molecular signatures of fertilizing spermatozoa in mice,' eLife, 2020
What About Methods for Men? A Qualitative Analysis of Attitudes Toward Male Contraception in Burkina Faso and Uganda
Alice F. Cartwright, Anna Lawton, Aurélie Brunie and Rebecca L. Callahan. 'What About Methods for Men? A Qualitative Analysis of Attitudes Toward Male Contraception in Burkina Faso and Uganda,' International Perspectives on Sexual and Reproductive Health , 2020, Vol. 46 (2020), pp. 153-162
Synthesis of 2-phenyl-5,6,7,8-tetrahydroquinoxaline derivatives and screening for P2X1-purinoreceptor antagonist activity in isolated preparations of rat vas deferens, for translation into a male contraceptive
Mathiew M, Dennis B, Bennetts F, Su E, Nguyen N, Botteon A, Baell J, Ventura S. 'Synthesis of 2-phenyl-5,6,7,8-tetrahydroquinoxaline derivatives and screening for P2X1-purinoreceptor antagonist activity in isolated preparations of rat vas deferens, for translation into a male contraceptive,' Biology of Reproduction, 2020.
The Impact of Di-2-Ethylhexyl Phthalate on Sperm Fertility
Liliya Gabelev Khasin, John Della Rosa, Natalie Petersen, Jacob Moeller, Lance J. Kriegsfeld, and Polina V. Lishko, ‘The Impact of Di-2-Ethylhexyl Phthalate on Sperm Fertility,’ Frontiers in Cell and Developmental Biology, 2020,
Optimization of Lead Compounds Into On-Demand, Non-Hormonal Contraceptives: Leveraging a Public-Private Drug Discovery Institute Collaboration
Balbach, Melanie, Makoto Fushimi, David J Huggins, Clemens Steegborn, Peter T Meinke, Lonny R Levin, et al., ‘Optimization of Lead Compounds into On-Demand, Nonhormonal Contraceptives: Leveraging a Public–Private Drug Discovery Institute Collaboration†’, Biology of Reproduction, 2020.
HIPK4 is Essential for Murine Spermiogenesis
J Aaron Crapster, Paul G Rack, Zane J Hellmann, Austen D Le, Christopher M Adams, Ryan D Leib, Joshua E Elias, John Perrino, Barry Behr, Yanfeng Li, Jennifer Lin, Hong Zeng, James K Chen. 'HIPK4 is Essential for Murine Spermiogenesis,' eLife 2020
External Publications
In this section, we highlight select publications that we feel are useful in developing a holistic understanding of the challenges and opportunities inherent to family planning and contraception, generally, and male contraception, specifically.
“Contraceptive technologies for global health: ethically getting to safe, effective and acceptable options for women and men” by John Townsend, Régine Sitruk-Ware, Saumya Rama Rao, and Jim Sailer
“Sexual orientation-related differences in contraceptive use: A brief report based on a cohort of adolescent and young women” by Brittany M. Charlton, Colleen A. Reynolds, Elizabeth Janiak, Amy D. DiVasta, Rachel K. Jones, Jorge E. Chavarro, Vishnudas Sarda, S. Bryn Austin
“Parents' experience of unintended childbearing: A qualitative study of factors that mitigate or exacerbate effects” by Megan L. Kavanaugh, Kathryn Kost, Lori Frohwirth, Isaac Maddow-Zimet, and Vivian Gor
“Are higher unintended pregnancy rates among minorities a result of disparate access to contraception?” by Michele Troutman, Saima Rafique, and Torie Comeaux Plowden
Kent, K., Johnston, M., Strump, N., & Garcia, T. X. (2020). Toward Development of the Male Pill: A Decade of Potential Non-hormonal Contraceptive Targets. Frontiers in Cell and Developmental Biology, 8, 61. https://doi.org/10.3389/fcell.2020.00061
Johnston, D. S., & Goldberg, E. (2020). Preclinical contraceptive development for men and women. Biology of Reproduction, 103(2), 147–156. https://doi.org/10.1093/biolre/ioaa076
Yuen, F., Nguyen, B. T., Swerdloff, R. S., & Wang, C. (2020). Continuing the search for a hormonal male contraceptive. Best Practice & Research. Clinical Obstetrics & Gynaecology, 66, 83–94. https://doi.org/10.1016/j.bpobgyn.2020.02.003
Khilwani, B., Badar, A., Ansari, A. S., & Lohiya, N. K. (2020). RISUG® as a male contraceptive: Journey from bench to bedside. Basic and Clinical Andrology, 30, 2. https://doi.org/10.1186/s12610-020-0099-1
Abbe, C., & Roxby, A. C. (2020). Assessing safety in hormonal male contraception: A critical appraisal of adverse events reported in a male contraceptive trial. BMJ Sexual & Reproductive Health, 46(2), 139–146. https://doi.org/10.1136/bmjsrh-2018-200206
Amory, J. K. (2016). Male contraception. Fertility and Sterility, 106(6), 1303–1309. https://doi.org/10.1016/j.fertnstert.2016.08.036
“Contraceptive technologies for global health: ethically getting to safe, effective and acceptable options for women and men” by John Townsend, Régine Sitruk-Ware, Saumya Rama Rao, and Jim Sailer
“Sexual orientation-related differences in contraceptive use: A brief report based on a cohort of adolescent and young women” by Brittany M. Charlton, Colleen A. Reynolds, Elizabeth Janiak, Amy D. DiVasta, Rachel K. Jones, Jorge E. Chavarro, Vishnudas Sarda, S. Bryn Austin
“Parents' experience of unintended childbearing: A qualitative study of factors that mitigate or exacerbate effects” by Megan L. Kavanaugh, Kathryn Kost, Lori Frohwirth, Isaac Maddow-Zimet, and Vivian Gor
“Are higher unintended pregnancy rates among minorities a result of disparate access to contraception?” by Michele Troutman, Saima Rafique, and Torie Comeaux Plowden
Kent, K., Johnston, M., Strump, N., & Garcia, T. X. (2020). Toward Development of the Male Pill: A Decade of Potential Non-hormonal Contraceptive Targets. Frontiers in Cell and Developmental Biology, 8, 61. https://doi.org/10.3389/fcell.2020.00061
Johnston, D. S., & Goldberg, E. (2020). Preclinical contraceptive development for men and women. Biology of Reproduction, 103(2), 147–156. https://doi.org/10.1093/biolre/ioaa076
Yuen, F., Nguyen, B. T., Swerdloff, R. S., & Wang, C. (2020). Continuing the search for a hormonal male contraceptive. Best Practice & Research. Clinical Obstetrics & Gynaecology, 66, 83–94. https://doi.org/10.1016/j.bpobgyn.2020.02.003
Khilwani, B., Badar, A., Ansari, A. S., & Lohiya, N. K. (2020). RISUG® as a male contraceptive: Journey from bench to bedside. Basic and Clinical Andrology, 30, 2. https://doi.org/10.1186/s12610-020-0099-1
Abbe, C., & Roxby, A. C. (2020). Assessing safety in hormonal male contraception: A critical appraisal of adverse events reported in a male contraceptive trial. BMJ Sexual & Reproductive Health, 46(2), 139–146. https://doi.org/10.1136/bmjsrh-2018-200206
Amory, J. K. (2016). Male contraception. Fertility and Sterility, 106(6), 1303–1309. https://doi.org/10.1016/j.fertnstert.2016.08.036
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