Market Publications
Consumer Research Study
Male Contraceptive Initiative led a study to identify unmet needs and satisfaction with current contraceptive methods among a sample of men across key market segments. To the best of our knowledge, this is the largest survey in the United States in the last ten years exclusive to sexually active men ages 18-44 to better understand their attitudes, needs and motivations regarding the future of male contraception as a family planning method.
Male Contraceptive Initiative led a study to identify unmet needs and satisfaction with current contraceptive methods among a sample of men across key market segments. To the best of our knowledge, this is the largest survey in the United States in the last ten years exclusive to sexually active men ages 18-44 to better understand their attitudes, needs and motivations regarding the future of male contraception as a family planning method.
Enhanced Discovery Scan
Male Contraceptive Initiative worked with YTH to explore the body of existing knowledge around male contraception and generate novel solutions for furthering effective development and user engagement in this area. This Executive Summary shares key findings from the study, as well as details on the study’s aims and methodology.
Male Contraceptive Initiative worked with YTH to explore the body of existing knowledge around male contraception and generate novel solutions for furthering effective development and user engagement in this area. This Executive Summary shares key findings from the study, as well as details on the study’s aims and methodology.
Scientific Publications
Vahdat, Heather L, Kevin Shane, and Logan M Nickels, "The Role of Team Science in the Future of Male Contraception†." Biology of Reproduction, 2020.
Campelia, Georgina D., Carmen Abbe, Logan M. Nickels, Evy McElmeel, and John K. Amory, '"Shared Risk": Reframing Risk Analysis in the Ethics of Novel Male Contraceptives', Contraception, 2020.
Dorman, Emily, et al. “Modeling the impact of novel male contraceptive methods on reductions in unintended pregnancies in Nigeria, South Africa, and the United States.” Contraception 97.1 (2018): 62-69.
MCI Publications
Male Contraception Ideation Event Report
MCI invited leaders in male contraception, and from other fields of practice to contribute their knowledge and experience to brainstorm potential solutions to the persistent challenges in the field of male contraceptive research and development over the course of a 3-day ideation event at the IDEO offices in San Francisco. This report shares details about and outcomes from the event.
MCI invited leaders in male contraception, and from other fields of practice to contribute their knowledge and experience to brainstorm potential solutions to the persistent challenges in the field of male contraceptive research and development over the course of a 3-day ideation event at the IDEO offices in San Francisco. This report shares details about and outcomes from the event.
Male Contraception Initiative’s 2019 Annual Report
MCI had a tremendous year in 2019 thanks to your generous support. This annual report shares details about all that we were able to accomplish together.
MCI had a tremendous year in 2019 thanks to your generous support. This annual report shares details about all that we were able to accomplish together.
MCI Grantee Publications
Male Contraceptive Initiative engages with and supports a diverse, international research community working to make new methods of non-hormonal, reversible male contraceptives a reality. Our grantees represent decades of experience in scientific enquiry that span multiple research areas. As such, there is an extensive body of work attributable to them. In this section, we highlight only the publications of our grantees that are directly attributable to MCI’s support.
Synthesis of 2-phenyl-5,6,7,8-tetrahydroquinoxaline derivatives and screening for P2X1-purinoreceptor antagonist activity in isolated preparations of rat vas deferens, for translation into a male contraceptive
Mathiew M, Dennis B, Bennetts F, Su E, Nguyen N, Botteon A, Baell J, Ventura S. 'Synthesis of 2-phenyl-5,6,7,8-tetrahydroquinoxaline derivatives and screening for P2X1-purinoreceptor antagonist activity in isolated preparations of rat vas deferens, for translation into a male contraceptive,' Biology of Reproduction, 2020.
The Impact of Di-2-Ethylhexyl Phthalate on Sperm Fertility
Liliya Gabelev Khasin, John Della Rosa, Natalie Petersen, Jacob Moeller, Lance J. Kriegsfeld, and Polina V. Lishko, ‘The Impact of Di-2-Ethylhexyl Phthalate on Sperm Fertility,’ Frontiers in Cell and Developmental Biology, 2020,
Optimization of Lead Compounds Into On-Demand, Non-Hormonal Contraceptives: Leveraging a Public-Private Drug Discovery Institute Collaboration
Balbach, Melanie, Makoto Fushimi, David J Huggins, Clemens Steegborn, Peter T Meinke, Lonny R Levin, et al., ‘Optimization of Lead Compounds into On-Demand, Nonhormonal Contraceptives: Leveraging a Public–Private Drug Discovery Institute Collaboration†’, Biology of Reproduction, 2020.
HIPK4 is Essential for Murine Spermiogenesis
J Aaron Crapster, Paul G Rack, Zane J Hellmann, Austen D Le, Christopher M Adams, Ryan D Leib, Joshua E Elias, John Perrino, Barry Behr, Yanfeng Li, Jennifer Lin, Hong Zeng, James K Chen. “HIPK4 is Essential for Murine Spermiogenesis”. eLife 2020
Synthesis of 2-phenyl-5,6,7,8-tetrahydroquinoxaline derivatives and screening for P2X1-purinoreceptor antagonist activity in isolated preparations of rat vas deferens, for translation into a male contraceptive
Mathiew M, Dennis B, Bennetts F, Su E, Nguyen N, Botteon A, Baell J, Ventura S. 'Synthesis of 2-phenyl-5,6,7,8-tetrahydroquinoxaline derivatives and screening for P2X1-purinoreceptor antagonist activity in isolated preparations of rat vas deferens, for translation into a male contraceptive,' Biology of Reproduction, 2020.
The Impact of Di-2-Ethylhexyl Phthalate on Sperm Fertility
Liliya Gabelev Khasin, John Della Rosa, Natalie Petersen, Jacob Moeller, Lance J. Kriegsfeld, and Polina V. Lishko, ‘The Impact of Di-2-Ethylhexyl Phthalate on Sperm Fertility,’ Frontiers in Cell and Developmental Biology, 2020,
Optimization of Lead Compounds Into On-Demand, Non-Hormonal Contraceptives: Leveraging a Public-Private Drug Discovery Institute Collaboration
Balbach, Melanie, Makoto Fushimi, David J Huggins, Clemens Steegborn, Peter T Meinke, Lonny R Levin, et al., ‘Optimization of Lead Compounds into On-Demand, Nonhormonal Contraceptives: Leveraging a Public–Private Drug Discovery Institute Collaboration†’, Biology of Reproduction, 2020.
HIPK4 is Essential for Murine Spermiogenesis
J Aaron Crapster, Paul G Rack, Zane J Hellmann, Austen D Le, Christopher M Adams, Ryan D Leib, Joshua E Elias, John Perrino, Barry Behr, Yanfeng Li, Jennifer Lin, Hong Zeng, James K Chen. “HIPK4 is Essential for Murine Spermiogenesis”. eLife 2020