The scrotum is a feature of the male reproductive system that hangs from the body at the front of the pelvis, between the legs. It is a sac of skin divided into two chambers, and it sits next to the upper thighs. The two compartments of the scrotum are distinguished externally by a middle ridge called the raphe. Internally, the raphe connects to a muscular partition, the septum, which serves to divide the scrotum into its two areas.

Male Contraceptive Initiative provides funding and advocacy support for the development of non-hormonal, reversible forms of male contraception. But what does “non-hormonal” mean? How do these methods differ from “hormonal” contraceptives? In this post, we share a primer on the difference between hormonal and non-hormonal contraception. (Please note that there is a mini-glossary at the end of the post that provides definitions for key terms featured in the post. Please visit the Glossary page on our website for additional terms and definitions.)

The human reproductive system is a complex set of intertwining factors, many of which are required for sustained fertility. By interrupting even a single one of these required processes, we can find new ways to create exciting non-hormonal contraceptives for men. One process is fertilization, or the joining of human egg and sperm to create a zygote. Fertilization is a prime target for male contraception because of its place as the last step in the reproductive chain.

The prostate is part of the male reproductive system. A walnut-sized gland located between the male bladder and the penis, the prostate sits just in front of the rectum. The urethra runs from the bladder to the penis, through the center of the prostate.​

Vasectomy and condoms are the only current options for male contraception. The most popular form of long-acting male contraception is a vasectomy. Unfortunately, vasectomies are not considered truly reversible. Reversal of a vasectomy is often expensive, and requires a long surgery by a specialized provider.